What grade did the USPSTF assign to screening for latent tuberculosis infection?

What grade did the USPSTF assign to screening for latent tuberculosis infection?

• A. Grade A
• B. Grade C
• C. Grade D
• D. Grade B

Answer: (D)

Grade B is the correct assignment. This means there is at least moderate certainty that screening for latent tuberculosis infection in people who are at increased risk provides a moderate to substantial net benefit. The recommendation targets groups with higher risk of exposure or progression, such as close contacts of someone with active TB, people born in or frequently visiting regions with high TB prevalence, and individuals who are immunocompromised (including HIV). Screening tests typically include the tuberculin skin test or an IGRA, and a positive result leads to further evaluation to exclude active TB and consideration of treatment to prevent progression to active disease. This broader screening is not recommended for the general population because the net benefit is not as favorable in low-risk groups.

Grade B is the correct assignment. This means there is at least moderate certainty that screening for latent tuberculosis infection in people who are at increased risk provides a moderate to substantial net benefit. The recommendation targets groups with higher risk of exposure or progression, such as close contacts of someone with active TB, people born in or frequently visiting regions with high TB prevalence, and individuals who are immunocompromised (including HIV). Screening tests typically include the tuberculin skin test or an IGRA, and a positive result leads to further evaluation to exclude active TB and consideration of treatment to prevent progression to active disease. This broader screening is not recommended for the general population because the net benefit is not as favorable in low-risk groups.